NFL Betting Lines: Week 10 Odds, Trends, and Top Matchups Preview

Week 10 in the NFL gets started Thursday night with the Seattle Seahawks at the Arizona Cardinals as a 6-point road underdog. Seattle has been rough on bettors with a 3-6 record against the spread in their last nine games, and a 2-6 ATS record in their last eight as a road favorite.

Arizona is a strong 6-3 straight up and ATS in their last nine as a home underdog, but they’re 2-6 ATS in their last eight games overall.

NFC North cellar dwellers meet up this week when the Chicago Bears host the Green Bay Packers as a 3-point favorite. Chicago has won four straight ATS and they’re 8-1 ATS in their last nine at home. Green Bay has lost three straight SU and ATS, but they’re 7-1 SU and 6-2 ATS in their last eight versus Chicago. As an underdog versus the Bears the Packers are 1-4 SU and 2-2-1 ATS in their last five.

The NFC North leading Minnesota Vikings are a 1.5-point road favorite this week at the Washington Redskins. Minnesota returns from their bye having won four in a row while going 3-1 ATS. On the road it’s a different story for the Vikings, as they are 2-6 SU and 1-7 ATS in their last eight. Washington is 1-4 ATS in their last five games and 1-5 ATS in their last six at home.

Two of the league’s worst face off this week when the San Francisco 49ers host the New York Giants as a 1-point underdog. New York is 1-8 SU and 3-6 ATS in their last nine and in the two games this season in which they were favored they lost both SU. The 49ers have lost 10 in a row SU while going 5-5 ATS. At home they’ve lost 11 straight at 2-9 ATS, and against the Giants they’re 2-6 SU and 3-5 ATS in their last eight.

The Los Angeles Chargers return from their bye as a 4-point road underdog versus the Jacksonville Jaguars. Los Angeles is 3-1 SU and ATS in their last four and they’ve won six straight SU and ATS versus the Jaguars. Jacksonville is a solid 8-3 ATS in their last 11 games, but strangely they are only 2-6 SU and ATS in their last eight at home.

On Sunday night the New England Patriots are a 7.5-point road favorite at the Denver Broncos. New England is also coming off their bye having won four straight at 3-1 ATS. As a road favorite the Patriots are 10-0 SU and 8-2 ATS in their last 10. Denver has lost four in a row SU and ATS, but as a home underdog they’re 5-1 SU and ATS in their last six games.

This week’s Monday nighter is the Miami Dolphins at the Carolina Panthers as an 8-point underdog. Miami is a horrible 3-13-1 ATS in their last 17 night games, but 4-1 SU and 5-0 ATS in their last five against the Panthers. Carolina can’t get it done at home with a 5-6 SU record and 3-6-2 ATS mark in their last 11, with five of those SU losses coming as the favorite.